A method for producing a monkey-derived embryonic stem cell comprising the
steps of carrying out fertilization by insemination by in vitro
fertilization or intracytoplasmic sperm injection using a monkey ovum and
monkey sperms, thereby giving a fertilized ovum, allowing the fertilized
ovum to differentiate into a blastocyst by in vitro culture, and
establishing an ES cell line using the blastocyst; the monkey ES cell
obtained by the method, a method for screening a reagent for specific
differentiation into cell or tissue by using the ES cell; and a
differentiated cell or differentiated tissue each differentiated from the
ES cell. According to the present invention, applications of the
embryonic stem cells to embryological studies clinical applications,
experimental models, and the like on primates, studies of diseases, are
expected.