In this application is the expression and purification of a recombinant
Plasmodium vivax (SalI) PvMSP-1 p42. The method of the present invention
produces a highly purified protein which retains folding and disulfide
bridging of the native molecule. The recombinant PvMSP-1 p42 is useful as
a diagnostic reagent, for use in antibody production, and as a vaccine.