Compositions comprising omega-3 fatty acids are provided, where the
compositions are useful for treating cardiovascular disease in patients
suffering from chronic kidney disease (CKD), preventing its further
progression, and treating underlying risk factors such as hypertension,
dyslipidemia, obesity and/or diabetes. Also provided are methods of using
the compositions to reduce the occurrence of or prevent major coronary
events, including myocardial infarctions, in patients with CKD.