The invention relates to oxadiazolones and to their physiologically
acceptable salts and physiologically functional derivatives showing
peroxisome proliferator activator receptor (PPAR) delta agonist activity
comprising compounds of formula I,
in which the R1-R7 substituents as well as the U, V, W, X Y and z radicals
are as defined herein, and their physiologically acceptable salts and
processes for their preparation. The compounds are suitable for the
treatment and/or prevention of disorders of fatty acid metabolism and
glucose utilization disorders as well as of disorders in which insulin
resistance is involved; neurodegenerative diseases and/or de-myelinating
disorders of the central and peripheral nervous systems and/or
neurological diseases involving neuro-inflammatory processes and/or other
peripheral neuropathies.