The present invention relates to biomaterials modified with
non-proteinaceous catalysts for the dismutation of superoxide, and
processes for making such materials. This modification may be by covalent
conjugation, copolymerization, or admixture of the non-proteinaceous
catalysts with the biomaterial. The resulting modified biomaterials
exhibit a marked decrease in inflammatory response and subsequent
degradation when placed in contact with vertebrate biological systems.