A method and apparatus to treat regions of a vessel is described. A
protein elastin-based polymer is released from the apparatus to coat the
vessel lining as a primary therapy or an adjunct therapy with the
delivery and deployment of a stent with or without drug coating. The
protein elastin-based polymer may include a triblock structure having an
elastin pentapeptide as the flanking block and a hydrophilic variant of
the pentapeptide as the middle block. Both the flanking and middle blocks
can be modified to change the structural and chemical properties of the
polymer. In particular, the protein elastin based polymer is adapted to
perform at least one of controlling release of a treatment agent,
stimulating endothelial cell growth and stabilizing the vulnerable plaque
to prevent rupture of the vulnerable plaque.