An unnatural amino acid including a phosphate mimicking group for
mimicking a phosphate group in phosphoamino acids and a protein
phosphatase modifying group for covalently binding protein phosphatases.
A probe for detecting disease including a phosphate mimicking group for
mimicking a phosphate group in phosphoamino acids and a protein
phosphatase modifying group for covalently binding protein phosphatases.
A method for detecting the presence of disease by administering the
unnatural amino acid, binding the unnatural amino acid with a
phosphatase, detecting a signal, and detecting the presence of disease. A
method of identifying a known protein phosphatase, and a method of
identifying an unknown protein phosphatase. A method of making the
unnatural amino acid.