This invention pertains to biocatalysts that are specifically targeted to bind pathogens, such as viruses, and to degrade components of pathogens in order to abrogate their pathogenicity, and to methods of preventing or treating infection by pathogenic organisms. The biocatalysts comprise a binding agent which specifically binds a surface component of a pathogen, for instance the gp120 viral coat protein of the Human Immunodeficiency Virus, and a catalytic moiety which degrades a component of the pathogen so that its pathogenicity is abrogated. The binding agent and the catalytic moiety are linked by chemical linkers or genetic engineering techniques.

Esta invenção pertence aos biocatalysts que são alvejados especificamente para ligar os pathogens, tais como vírus, e para degradar os componentes dos pathogens revogam seu pathogenicity, e aos métodos de impedir ou de tratar a infecção por organismos pathogenic. Os biocatalysts compreendem um agente obrigatório que ligue especificamente um componente de superfície de um pathogen, por exemplo a proteína viral do revestimento gp120 do vírus humano do immunodeficiency, e de um moiety catalytic que degrade um componente do pathogen de modo que seu pathogenicity seja revogado. O agente obrigatório e o moiety catalytic são ligados por linkers químicos ou por técnicas da engenharia genetic.

 
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