A novel cell cycle regulatory gene called 5'ALT is disclosed. Methods for determining mutations or polymorphisms in 5'ALT or 5'ALT regulated genes in tissues are also provided. Novel 5'ALT-p16 and 5'ALT-p15 transcripts and truncated expression products are also described.

Een nieuw regelgevend gen van de celcyclus genoemd wordt 5'ALT onthuld. De methodes om veranderingen of polymorfisme in 5'ALT of 5'ALT geregelde genen in weefsels worden te bepalen ook verstrekt. De nieuwe afschriften 5'alt-p16 en 5'alt-p15 en de beknotte uitdrukkingsproducten worden ook beschreven.

 
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