The present invention provides improved oral dosage form formulations of
efavirenz that are useful in the inhibition of human immunodeficiency
virus (HIV), the prevention or treatment of infection by HIV, and in the
treatment of the resulting acquired immune deficiency syndrome (AIDS). In
particular, the present invention relates to compressed tablets or
capsules comprising efavirenz that contain one or more disintegrants that
enhance the dissolution rate of the efavirenz in the gastrointestinal
tract thereby improving the rate and extent of absorption of efavirenz in
the body. The present invention also relates to the process of making such
tablets or capsules.