The present invention is directed to compounds which inhibit farnesyl-protein transferas (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.

Присытствыющий вымысел направлен к смесям блокируют transferas фарнесыл-proteina (FTase) и farnesylation протеина Ras oncogene. Вымысел более добавочно направлен к хемотерапевтическим составам содержа смеси этих вымысла и методов для блокировать трансферазу фарнесыл-proteina и farnesylation протеина Ras oncogene.