A class of benzopyrans, benzothiopyrans, dihydroquinolines, dihydronaphthalenes, and analogs thereof, is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular interest are defined by Formula I' ##STR1## wherein X, A.sup.1, A.sup.2, A.sup.3, A.sup.4, R, R", R.sup.1 and R.sup.2 are as described in the specification.

Uma classe dos benzopyrans, dos benzothiopyrans, dos dihydroquinolines, dos dihydronaphthalenes, e dos analogs disso, é descrita para o uso em disorders mediados cyclooxygenase-2 de tratamento. Os compostos do interesse particular são definidos pelo ## do ## STR1 de Fórmula I' wherein X, A.sup.1, A.sup.2, A.sup.3, A.sup.4, R, R ", R.sup.1 e R.sup.2 são como descritos na especificação.