A mixed liposome pharmaceutical formulation with multilamellar vesicles is provided. The formulation comprises a pharmaceutical agent, water, an alkali metal alkyl sulfate, at least one membrane mimetic amphiphile, and at least one phospholipid. When aerosol delivery is intended, the formulation also comprises a propellant and a phenol. A metered dose dispenser containing the formulation, as well as a method of administering the formulation, are also provided.

Um formulation pharmaceutical do liposome misturado com vesicles multilamellar é fornecido. O formulation compreende um agente pharmaceutical, a água, um sulfate alkyl alcalino, ao menos um amphiphile mimetic da membrana, e ao menos um phospholipid. Quando a entrega do aerossol é pretendida, o formulation compreende também um propulsor e um phenol. Um distribuidor metered do dose que contem o formulation, as.well.as um método de administrar o formulation, é fornecido também.