A molecular detection device including a support member (36) and a plurality of molecular receptors (34) arranged at a plurality of sites of the support member (36). In a first aspect, the molecular receptors (34) are arranged in accordance with a mapping selected from the group consisting of a random mapping and a pseudorandom mapping. In a second aspect, data associated with the mapping is written to a member associated with the support member (36). In a third aspect, the molecular receptors (34) includes a first plurality of molecular receptors germane to an application and at least one molecular receptor extraneous to the application.