The present invention provides nucleic acid and amino acid sequence of the novel I-1 and I-2 polypeptides, which are associated with human inflammatory bowel disease (IBD). Methods of diagnosing and treating inflammatory bowel disease using the IBD-associated I-1 and I-2 antigens also are provided.

A invenção atual fornece a seqüência do ácido nucleic e do amino-ácido dos polypeptides I-1 e I-2 da novela, que são associados com a doença inflammatory humana do bowel (IBD). Os métodos de diagnosticar e de tratar a doença inflammatory do bowel usando os antígenos I-1 e I-2 IBD-associados são fornecidos também.

 
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