There is a structure of a front end portion of a front fender in a vehicle, in which the front fender has an outer surface portion, a vertical surface portion formed downward from an inner end of the outer surface portion and a flange formed inward from a lower end of the vertical surface portion. The structure is provided with an overhang portion formed by inward curving the outer surface portion and the vertical surface portion, and a mounting portion which is formed in a front end portion of the flange so as to be positioned immediately after the overhang portion and to which corresponding one of both end portions of a radiator core upper is mounted. And specifically, the mounting portion is at a position lower than the overhang portion.