An apparatus and method for measuring indicator concentration time curves optically from a living organism using a single wavelength, by comparing the optical density before and after injection of the indicator and by selectively utilizing the values of the concentration of blood hemoglobin, blood oxygen saturation, or the mean optical pathlength in the computation. Whereby, physiological parameters such as cardiac output, blood flow and blood volume can be calculated by analyzing the indicator concentration time curves.

 
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~ 00025