The invention relates to water soluble antitumor analogs of paclitaxel of formula (I) wherein R.sub.1 =C(O)CH.sub.2 CH(OH)COOX, R.sub.2 =H, C(O)CH.sub.2 CH(OH)COOX, X=H, Li, Na or any other pharmaceutically acceptable counterion, as well as to a pharmaceutical composition comprising an antineoplastically effective amount of such analogs as an active ingredient.

La invención se relaciona con los análogos antitumor solubles en agua del paclitaxel del fórmula (i) en donde R.sub.1 = C(O)CH.sub.2 CH(OH)COOX, R.sub.2 = H, C(O)CH.sub.2 CH(OH)COOX, X=H, li, Na o cualquier otro counterion farmacéutico aceptable, así como con una composición farmacéutica que abarca una cantidad antineoplastically eficaz de los análogos tales como un ingrediente activo.

 
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