An apparatus for identifying the location of a photon source within an imaging area and which generates photons having energies within a known energy range, the apparatus including two oppositely facing cameras disposed on opposite sides of the imaging area, each camera including a first detector unit which causes scattering when a photon enters the unit and generates signals indicative of the scattering event location, energy and time and a second detector unit which absorbs the scattered photon and generates signals indicative of the absorption event energy and time, the generated signals are then mathematically combined to determine the location of the source. Also a Compton camera including a first detector unit which is anatomically configured to generally mirror the external surface of a portion of a patient including an object to be imaged, a second detector unit positioned outside an imaging area to receive scattered photons from the first unit.