The present patent describes a three-dimensional interconnected open cell
porous foams that have a gradient in composition and/or microstructure
through one or more directions. These foams can be made from a blend of
absorbable and biocompatible polymers that are formed into foams having a
compositional gradient transitioning from predominately one polymeric
material to predominately a second polymeric material. These gradient
foams are particularly well suited to tissue engineering applications and
can be designed to mimic tissue transition or interface zones.