Compounds having Formula 2 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids. ##STR1##

Compone avere formula 2 in cui i simboli hanno il significato definito nella specifica sono inibitori dell'enzima del citocromo P450RAI (viscoelastico acido retinoic) e sono usati per le malattie trattanti sensibli a reagire al trattamento dai retinoids. ## del ## STR1