New injectable, in situ crosslinkable biodegradable polymer composites
comprise poly(propylene fumarate) (PPF), poly(ethylene
glycol)-dimethacrylate (PEG-DMA), an, optionally, .beta.-tricalcium
phosphate (.beta.-TCP). A method for controlling the crosslinking
characteristics of the composites, including the maximum crosslinking
temperature and the gel point, as well as the properties of the cross
linked composites such as the compressive strength and modulus and the
water holding capacity, is disclosed.
Injectable novos, em compostos biodegradable crosslinkable do polímero do situ compreendem o fumarate) do poly(propylene (PPF), o glycol)-dimethacrylate do poly(ethylene (PEG-DMA), opcionalmente, o phosphate beta.-beta.-tricalcium (beta.-TCP). Um método para controlar as características crosslinking dos compostos, including a temperatura crosslinking máxima e o ponto do gel, assim como as propriedades dos compostos ligados transversais tais como a força compressive e o modulus e a água que prende a capacidade, é divulgado.