The present invention provides a method of inhibiting angiogenesis within a tissue by providing exogenous SLED to cells associated with the tissue. The presence of exogenous SLED inhibits angiogenesis within the tissue, in part by interfering with the ability of vascular endothelia to expand within the tissue. The invention also provides a method for determining the severity of a tumor be assaying for the presence of SLED within the tumor. To facilitate the inventive methods, the present invention provides pharmaceutical compositions including sources of SLED.

A invenção atual fornece um método de inibir o angiogenesis dentro de um tecido fornecendo o TRENÓ exogenous às pilhas associadas com o tecido. A presença do TRENÓ exogenous inibe o angiogenesis dentro do tecido, na parte interferindo com a abilidade do endothelia vascular de expandir dentro do tecido. A invenção fornece também um método determinando a severidade de um tumor assaying para a presença do TRENÓ dentro do tumor. Para facilitar os métodos inventive, a invenção atual fornece composições pharmaceutical including fontes do TRENÓ.

 
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