A docking station for use with an environmental monitoring instrument to provide predictive diagnostic information. The docking station is connected, typically via the Internet, to a remote service center, and exposure data, calibration data and diagnostic data are communicated from the instrument to the docking station and from the docking station to the service center. Mathematical analysis of the collected data from all available sources is performed at the service center and predictive warnings are generated to alert the users of potential instrument faults, thus allowing preemptive maintenance. The analysis methods include principle component analysis and other statistical methods, fuzzy logic and neural networks. This docking station can be used with monitoring instruments for water quality, pollution control, indoor air quality and breathing air quality.