Compounds of this formula ##STR1## are useful for treating or preventing, obesity, breast cancer, osteoporosis, endometriosis, cardiovascular disease and prostatic disease.

Os compostos deste ## do ## STR1 da fórmula são úteis para o tratamento ou impedir, o obesity, o cancer de peito, o osteoporosis, o endometriosis, doença cardiovascular e doença prostatic.