The 4-hydroxyquinoline compounds and/or tautomers thereof, notably
4-hydroxy-5,7-dichchloroquinoline, are synthesized in very high yields by
hydrolyzing/decarboxylating a 4-hydroxyquinolinecarboxylic acid ester in
the presence of water, whether in liquid or vapor state, but in the
absence of any catalyst for such reaction(s).
Смеси 4-hydroxyquinoline and/or tautomers thereof, знатно 4-hydroxy-5,7-dichchloroquinoline, в очень высоких выходах hydrolyzing/decarboxylating кисловочный эстер 4-hydroxyquinolinecarboxylic in the presence of вода, синтезированы ли в положении жидкости или пара, но в отсутствии любого катализатора для такого reaction(s).