The subject invention involves compounds having the structure: ##STR1## wherein the C.sub..alpha. --N.sub..beta., C.sub.5 -C.sub.6, and C.sub.6 -C.sub.7 bonds are each single or double bonds, except that both C.sub.5 -C.sub.6, and C.sub.6 -C.sub.7 are double bonds; R1 is selected from hydrogen, alkyl, aryl, and heterocycle; R2-R15 are independently selected from hydrogen and other substituents; and pharmaceutically-acceptable forms thereof. The subject invention also involves pharmaceutical compositions containing such compounds, and methods for treating or preventing diseases and disorders using such compounds.

Subject вымысел включает смеси имея структуру: ## ## STR1 при котором C.sub..alpha. -- N.sub..beta., C.sub.5 - C.sub.6, и C.sub.6 - скрепления C.sub.7 каждые single or double скрепления, except that оба C.sub.5 - C.sub.6, и C.sub.6 - C.sub.7 будут двойными скреплениями; R1 выбрано от водопода, алкила, арила, и heterocycle; R2-R15 независимо выбраны от водопода и других заместителей; и pharmaceutically-acceptable формы thereof. Subject вымысел также включает фармацевтические составы содержа такие смеси, и методы для обрабатывать или предотвращать заболевания и разлады использующ такие смеси.

 
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