This invention is directed to novel tricyclic ICE/ced-3 family inhibitor compounds. The invention is also directed to pharmaceutical compositions of such tricyclic compounds, plus the use of such compositions in the treatment of patients suffering inflammatory, autoimmune and neurodegenerative diseases, and for the prevention of ischemic injury.

 
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< C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases

< Mch4 and Mch5, apoptotic protease, nucleic acids encoding and methods of use

> Human bad polypeptides, encoding nucleic acids and methods of use

> MCH4 and MCH5, apoptotic proteases

~ 00060