The present invention provides methods for expanding and increasing survival of hematopoietic cell populations, for prolonging viability of an organ for transplantation, and enhancing bioproduction, using interleukin-1.beta.-converting enzyme (ICE)/CED-3 family inhibitors. Exemplary compounds useful in the methods of the invention are provided herein.

La actual invención proporciona los métodos para ampliar y aumentar la supervivencia de las poblaciones hematopoietic de la célula, para prolongar viabilidad de un órgano para el trasplante, y realzar el bioproduction, usando la enzima de interleukin-1.beta.-converting (inhibidores de la familia ICE)/CED-3. Los compuestos ejemplares útiles en los métodos de la invención se proporcionan adjunto.

 
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