A novel human metabotropic glutamate receptor (mGluR) protein is identified, sequenced, and cloned. The receptor may be used to screen for compounds that modulate the activity of the mGluR. The recombinant mGluR as well as compounds that modulate mGluR activity may be used in the diagnosis and treatment of neurological disorders and diseases.

Een nieuwe menselijke proteïne metabotropic van de glutamaatreceptor (mGluR) wordt geïdentificeerd, gerangschikt en gekloond. De receptor kan aan het scherm voor samenstellingen worden gebruikt die de activiteit van mGluR moduleren. Recombinante mGluR evenals de samenstellingen die activiteit moduleren mGluR kunnen in de diagnose en de behandeling van neurologische wanorde en ziekten worden gebruikt.

 
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