This invention provides, non-peptide inhibitors of matrix metalloproteinases (e.g. gelatinases, stromelysins and collagenases) and TNF-.alpha. converting enzyme (TACE. tumor necrosis factor-.alpha. converting enzyme) which arc useful for the treatment of diseases in which these enzymes are implicated.

Diese Erfindung stellt, Nichtpeptid Hemmnisse von Matrix metalloproteinases (z.B. gelatinases, stromelysins und Kollagenbildungen) und TNF-.alpha. von umwandelndem Enzym zur Verfügung (TACE. Tumornekrose factor-.alpha. umwandelndes Enzym) welcher Bogen nützlich für die Behandlung der Krankheiten, in denen diese Enzyme impliziert werden.
 
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