The present invention is related to a novel intermediates and processes
which are useful in the preparation of certain antihistaminic piperidine
derivatives of the formula
##STR1##
wherein
W represents --C(.dbd.O)-- or --CH(OH)--;
R.sub.1 represents hydrogen or hydroxy;
R.sub.2 represents hydrogen;
R.sub.1 and R.sub.2 taken together form a second bond between the carbon
atoms bearing R.sub.1 and R.sub.2 ;
n is an integer of from 1 to 5;
m is an integer 0 or 1;
R.sub.3 is --COOH or --COOalkyl wherein the alkyl moiety has from 1 to 6
carbon atoms and is straight or branched each of A is hydrogen or hydroxy;
and
pharmaceutically acceptable salts and individual optical isomers thereof,
with the proviso that where R.sub.1 and R.sub.2 are taken to form a second
bond between the carbon atoms R.sub.1 and R.sub.2 or where R.sub.1
represented hydroxy integer 0.