Method of treating leukemia, inhibiting the growth or proliferation of
leukemic cells or extending the life span of a animal having leukemia are
disclosed. The methods comprise the step of treating the leukemia with an
effective amount of a compound of the Formula I
##STR1##
or a pharmaceutically acceptable salt or prodrug form thereof, wherein:
X is hydrogen, halogen or alkyl of less than 7 carbon atoms;
n is a positive integer of less than 4;
Y is hydrogen, chlorine, nitro, methyl or ethyl;
R is hydrogen or an alkyl group of from 1 to 8 carbon atoms, alkylcarbamyl;
R.sub.2 is 4-thiazolyl or NHCOOR.sub.1 ; and
R.sub.1 is an aliphatic hydrocarbon of less than 7 carbon atoms.
A chemotherapeutic agent and/or potentiator can be used in conjunction with
the compound of the Formula I.