The present invention provides for methods of typing a melanocytic neoplasm, in particular for classifying a Spitz nevus. The methods comprise detecting in a tumor sample the presence of an increase in copy number of the whole chromosome 11p arm, particularly the presence of an 11p isochromosome, which is associated with the presence of a Spitz nevus. The invention further provides methods of typing a melanocytic neoplasm by detecting the presence of a mutated H-RAS gene, which is also associated with the presence of a Spitz nevus.

A invenção atual fornece para métodos de datilografar um neoplasm melanocytic, no detalhe para classificar um nevus de Spitz. Os métodos compreendem detectar em uma amostra do tumor a presença de um aumento no número do braço inteiro do chromosome 11p, particularmente a presença da cópia de um 11p isochromosome, que seja associado com a presença de um nevus de Spitz. A invenção mais adicional fornece métodos de datilografar um neoplasm melanocytic detectando a presença de um gene mutated de H-RAS, que seja associado também com a presença de um nevus de Spitz.

 
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