The invention provides transgenic non-human animals and transgenic non-human mammalian cells harboring a transgene encoding an APP polypeptide comprising the Swedish mutation.

A invenção fornece animais non-human transgenic e as pilhas mammalian non-human transgenic que abrigam um transgene que codifica um polypeptide do APP que compreende o mutation sueco.
 
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> Nucleic acid encoding a phosphatase 2C that interacts with Fe 65

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