A human VEGF-related protein (VRP) has been identified and isolated that binds to, and stimulates the phosphorylation of, the receptor tyrosine kinase Flt4. The VRP is postulated to be a third member of the VEGF protein family. Also provided are antibodies that bind to VRP and neutralize a biological activity of VRP, compositions containing the VRP or antibody, methods of use, chimeric polypeptides, and a signal polypeptide for VRP.

 
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< Replicon based activation of endogenous genes

< VECTOR MODIFIED BY SEQUENCE CODING FOR A SEQUENCE OF AMINO ACIDS CONTAINED IN A MAMMALIAN PROTEIN HAVING THE BIOLOGICAL ACTIVITY OF A MEMBRANE RECEPTOR, EXPRESSION OF THIS SEQUENCE IN TRANSFORMED UNICELLULAR CULTURES BY MEANS OF THIS VECTOR, PROCEDURE FOR STUDYING LIGANDS RECOGNIZING THESE RECEPTORS

> Small organic molecule regulators of cell proliferation

> Vitronectin receptor antagonists
~ 00075