Imido and amido substituted alkanohydroxamic acids reduce the levels of TNF.alpha. and inhibit phosphodiesterase in a mammal. A typical embodiment is 3-(3-cyclopentyloxy-4-methoxyphenyl)-N-hydroxy-3-phthalimidopropionamide.

Imido e gli acidi alkanohydroxamic sostituiti amidi riducono i livelli di TNF.alpha. ed inibiscono la fosfodiesterasi in un mammifero. Un incorporamento tipico è 3-(3-cyclopentyloxy-4-methoxyphenyl)-N-hydroxy-3-phthalimidopropionamide.