A novel subtype of the P.sub.2 -purinergic receptor, referred to as the P.sub.2U2 receptor, is disclosed. This receptor is activated by four of its agonists in the following order of specificity: UTP>UDP>ADP>ATP. Nucleic acids encoding the receptor, antibodies that bind to the receptor and associated screening and therapeutic methods also are disclosed.

Een nieuw subtype van P.sub.2 - purinergic receptor, dat als receptor P.sub.2U2 wordt bedoeld, wordt onthuld. Deze receptor wordt geactiveerd door vier van zijn agonists in de volgende orde van specificiteit: ADP UTP UDP ATP. Nucleic zuren die de receptor, antilichamen coderen die aan de receptor en de bijbehorende onderzoek en therapeutische methodes ook binden worden onthuld.

 
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