A device and methods are described for a non-invasive transnasal and transocular drug delivery to the central nervous system using iontophoresis technology. By delivered through the olfactory nerve and the optical nerve, a biologically active substance of interest can be enhanced to be delivered into the CNS and CSF and bypassing the blood-brain barrier. Such drug delivery system can also be enhanced by using phonophoresis and other enhancement techniques.

Um dispositivo e os métodos são descritos para uma entrega transnasal e transocular non-invasive da droga ao sistema nervoso central usando a tecnologia do iontophoresis. Pelo entregado através do nervo olfactory e do nervo ótico, uma substância biològica ativa do interesse pode ser realçada para ser entregado no CNS e no CSF e em contornear a barreira blood-brain. Tal sistema da entrega da droga pode também ser realçado usando o phonophoresis e as outras técnicas do realce.

 
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