Formulations for hydrophobic pharmaceutical agents

   
   

The present invention features formulations, including liquid, semi-solid or solid pharmaceutical formulations, that improve the oral bioavailability of hydrophobic pharmaceutical agents, such as quinazoline-, nitrothiazole-, and indolinone-based compounds. Also featured are formulations for parenteral delivery of such hydrophobic pharmaceutical agents, as well as methods of making and using both types of formulations.

L'invenzione del presente caratterizza le formulazioni farmaceutiche semisolide o solide di formulazioni, compreso liquido, che migliorano la biodisponibilità orale degli agenti farmaceutici idrofobi, quale chinazolina -, nitrothiazole - ed i residui indolinone-basati. Inoltre sono descritte le formulazioni per la consegna parenterale di tali agenti farmaceutici idrofobi, così come i metodi di fabbricazione ed usando degli entrambi i tipi delle formulazioni.

 
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