Synthetic HIV gag genes

   
   

Synthetic DNA molecules encoding HIV gag and modifications of HIV gag are provided. The codons of the synthetic molecules are codons preferred by the projected host cell. The synthetic molecules may be used as a polynucleotide vaccine which provides effective immunoprophylaxis against HIV infection through stimulation of neutralizing antibody and cell-mediated immunity.

As moléculas sintéticas do DNA que codificam a mordaça do HIV e as modificações da mordaça do HIV são fornecidas. Os codons das moléculas sintéticas são codons preferidos pela pilha de anfitrião projetada. As moléculas sintéticas podem ser usadas como uma vacina do polynucleotide que forneça o immunoprophylaxis eficaz de encontro à infecção de HIV com o stimulation do antibody neutralizando e do immunity cell-mediated.

 
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