A bone growth-promoting composition is provided comprising hyaluronic acid
and a growth factor. The composition has a viscosity and biodegradability
sufficient to persist at an intra-articular site of desired bone growth
for a period of time sufficient to promote the bone growth. Preferably
hyaluronic acid is used in a composition range of 0.1-4% by weight and
preferred growth factor is bFGF, present in a concentration range of about
10.sup.-6 to 100 mg/ml.
