The invention relates to pharmaceutically active substances from the group
comprising midazolam and compounds with a methyl-substituted nitrogen atom
that is the ring atom of a nitrogenous heterocycle. These substances are
used to reduce the oxygen consumption during a physical activity. They can
be administered together with an effective amount of D-glucose, D-maltose,
ethanol, a glucogenic amine, a glucogenic amino acid or an amino acid
metabolizable via glyoxylate or a dipeptide or a pharmaceutically
acceptable salt of such an amino acid and an effective amount of thiamine,
of a pharmaceutically acceptable thiamine salt or of a combination of
folic acid and cyanocobalamine, with the proviso that the third component
is thiamine or a pharmaceutically acceptable thiamine salt if the second
component is D-glucose, D-maltose, a glucogenic amine, a glucogenic amino
acid non-metabolizable via glyoxylate, or a dipeptide or a
pharmaceutically acceptable salt of such an amino acid.