Method of treatment using humanized anti-CD11a antibodies

   
   

Humanized anti-CD11a antibodies and various uses therefor are disclosed. The humanized anti-CD11a antibody may bind specifically to human CD11a I-domain, have an IC50(nM) value of no more than about 1 nM for preventing adhesion of Jurkat cells to normal human epidermal keratinocytes expressing ICAM-1, and/or an IC50 (nM) value of no more than about 1 nM in the mixed lymphocyte response assay.

Humanized антитела anti-CD11a и различные пользы therefor показаны. Humanized антитело anti-CD11a может связать специфически к людскому Я-domenu CD11a, имеет IC50(nM) значение of no больше чем около 1 nM для предотвращая прилипания клеток Jurkat к нормальным людским эпидермическим keratinocytes выражая ICAM-1, and/or (nM) значение IC50 of no больше чем около 1 nM в смешанном assay реакции лимфоцита.

 
Web www.patentalert.com

< Agents that stimulate therapeutic angiogenesis and techniques and devices that enable their delivery

< Low ionic strength method and composition for reducing bacterial attachment to biomaterials

> Low and high voltage electrical heating devices

> Batch-fabricated gradient and RF coils for submicrometer resolution magnetic resonance imaging and manipulation

~ 00104