The invention provides isolated NPR1 nucleic acids and their encoded
proteins. The present invention provides methods and compositions relating
to altering NPR1 concentration and/or composition of plants. The invention
further provides recombinant expression cassettes, host cells, and
transgenic plants. Additionally, the present invention provides NPR1
promoter elements capable of initiating constitutive expression in a plant
expression constructs comprising them, cells, plants and seeds comprising
the constructs, and methods of using them to express heterologous nucleic
acids in a plant. Further, the present invention provides for methods for
screening putative activators of a plant resistance pathway.