The present invention relates to a method for preventing or treating of
cartilage related diseases, such as osteoarthritis, rheumatoid arthritis,
articular cartilage damage, multiple chondritis, osteochondrosis, etc.,
which comprises administering an effective amount of calcium L-threonate
to a subject in need of such prevention or treatment. It had been
demonstrated by experiments that calcium L-threonate could improve
significantly the positive expression percentage of collagen I mRNA in the
chondrocyte and osteoblast, improved significantly the positive expression
percentage of articular cartilage and epiphyseal cartilage, facilitated
the growth of chondrocyte, increased the quantity of bone collagen, and
promoted the formation of bone and cartilage matrix and the synthesis of
proteoglycan. It could also promote the formation of bone nourishing blood
vessels and improve the microcirculation of bone.
