High affinity TGF.beta. nucleic acid ligands and inhibitors

   
   

Methods are described for the identification and preparation of high-affinity nucleic acid ligands to TGF.beta.2. Included in the invention are specific RNA ligands to TGF.beta.2 identified by the SELEX method. Also included are RNA ligands that inhibit the interaction of TGF.beta.2 with its receptor.

Los métodos se describen para la identificación y la preparación de los ligands del ácido nucleic de la alto-afinidad a TGF.beta.2. Se incluyen en la invención los ligands específicos del RNA a TGF.beta.2 identificado por el método de SELEX. También se incluyen los ligands del RNA que inhiben la interacción de TGF.beta.2 con su receptor.

 
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