The present invention relates to
(-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane and pharmaceutically
acceptable salts thereof, compositions comprising
(-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically
acceptable salt thereof, and methods for treating or preventing a disorder
alleviated by inhibiting dopamine reuptake. In one embodiment, the
disorder is attention-deficit disorder, depression, obesity, Parkinson's
disease, a tic disorder, or an addictive disorder. The
(-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or pharmaceutically
acceptable salt thereof is preferably substantially free of its
corresponding (+)-enantiomer.
A invenção atual relaciona-se a (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane e pharmaceutically sais aceitáveis disso, compreender das composições (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane ou um sal pharmaceutically aceitável disso, e métodos para tratar ou impedir um disorder aliviado inibindo o reuptake do dopamine. Em uma incorporação, o disorder é disorder do atenção-deficit, depression, obesity, doença de Parkinson, um disorder tic, ou um disorder addictive. (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane ou pharmaceutically sal aceitável disso está preferivelmente substancialmente livre de seu corresponder (+)-enantiomer.