A series of aryl piperazine compounds of the formula:
##STR1##
or the pharmaceutically acceptable salts thereof, are effective
pharmaceuticals for the treatment of conditions related to or affected by
the serotonin 1.sub.A receptor; the compounds are particularly effective
antagonists at that receptor, and are particularly useful for alleviating
the symptoms of nicotine and tobacco withdrawal.
Uma série de compostos aryl do piperazine da fórmula: ## do ## STR1 ou os sais pharmaceutically aceitáveis disso, são pharmaceuticals eficazes para o tratamento das circunstâncias relacionadas a ou afetadas pelo receptor do serotonin 1.sub.A; os compostos são particularmente antagonistas eficazes nesse receptor, e são particularmente úteis para aliviar os sintomas do nicotine e da retirada do tabaco.
