The invention relates to novel nucleic acid fragments encoding polypeptides
which are capable of mediating contact between enamel and cell surface.
The invention also relates to expression vectors containing the nucleic
acid fragments according to the invention for production of the protein,
organisms containing said expression vector, methods for producing the
polypeptide, compositions comprising the polypeptides, antibodies or
antibody fragments recognizing the polypeptides, and methods for treating
various hard tissue diseases or disorders.